THE PROGRAMME
OF PRACTICAL SEMINARS
“Phthisiology” for dental students
№
Topic
Hours
1.
The causative agent of tuberculosis
(TB), structure, metabolism, pathogenesis and molecular determinants of
virulence. Classification of Mycobacterium species. Epidemiological indicators
of TB burden. Global and national TB epidemiology. TB
transmission. Pathogenesis of tuberculosis. Immunity to TB. Clinical
classification of tuberculosis. Latent TB infection. Risk groups. Primary and
Post Primary TB.
4
2.
Clinical presentation of TB. Cough
management in primary care settings. Laboratory diagnostics of tuberculosis.
Sputum AFB microscopy. Rules of specimen’s collection. Bacteriological and
molecular methods of detection of M. tuberculosis. Benefits and drawbacks of
phenotypic and genotypic lab methods. Chest radiography, CT scanning and MRI
in TB detection. Descriptive terminology and types of imaging. Typical
and atypical presentations of Pulmonary TB on a Chest X-Ray. Tuberculin Skin
Test (TST). Interferon-Gamma Release Assays (IGRA). Interpretation of TST and
IGRA results. Other tools to confirm TB diagnosis.
Life-threatening complications of TB requiring Intensive Care Unit (ICU)
admission: pneumothorax, lung hemorrhage, airway obstruction, anaphylaxis.
4
3.
Pulmonary, extrapulmonary, and combined
localisation of tuberculosis. Generalised (milliary) TB. TB meningitis. TB of
peripheral lymph nodes. Tuberculous pleurisy.
TB in children. BCG vaccination.
Differences of TB disease in vaccinated and non-vaccinated children.
4
4.
Clinical management of tuberculosis.
Anti-TB medicines. Standardised and individualised regimens of treatment.
Drug-resistant strains of M. tuberculosis: mono-, poly-, MDR and XDR-TB. Active
monitoring and management of adverse events of anti-TB drugs. Recording
standardized treatment outcomes. Fighting TB stigma and
discrimination.
4
5.
Management of TB/HIV co-infection.
Antiretroviral Therapy for Patients with HIV and Active Tuberculosis. Tuberculosis-Associated
Immune Reconstitution Inflammatory Syndrome. Surgical treatment of TB.
Palliative care. Directly Observed Therapy.. Adherence to treatment.
4
6.
Prevention of tuberculosis. Infection
Control: administrative, engineering and respiratory protection levels.
Contact Tracing. BCG Vaccination. Preventive chemotherapy. TB health care
policy.
4
7.
BCG Vaccination. Management and outcome
of Bacille Calmette-Guérin vaccine adverse reactions. Preventive Therapy for
Tuberculous Infection. When Is the Benefit Worth the Risk and
Cost?
4
Module
Total
28
№
|
Topic
|
Hours
|
1.
|
The causative agent of tuberculosis
(TB), structure, metabolism, pathogenesis and molecular determinants of
virulence. Classification of Mycobacterium species. Epidemiological indicators
of TB burden. Global and national TB epidemiology. TB
transmission. Pathogenesis of tuberculosis. Immunity to TB. Clinical
classification of tuberculosis. Latent TB infection. Risk groups. Primary and
Post Primary TB.
|
4
|
2.
|
Clinical presentation of TB. Cough
management in primary care settings. Laboratory diagnostics of tuberculosis.
Sputum AFB microscopy. Rules of specimen’s collection. Bacteriological and
molecular methods of detection of M. tuberculosis. Benefits and drawbacks of
phenotypic and genotypic lab methods. Chest radiography, CT scanning and MRI
in TB detection. Descriptive terminology and types of imaging. Typical
and atypical presentations of Pulmonary TB on a Chest X-Ray. Tuberculin Skin
Test (TST). Interferon-Gamma Release Assays (IGRA). Interpretation of TST and
IGRA results. Other tools to confirm TB diagnosis.
Life-threatening complications of TB requiring Intensive Care Unit (ICU)
admission: pneumothorax, lung hemorrhage, airway obstruction, anaphylaxis.
|
4
|
3.
|
Pulmonary, extrapulmonary, and combined
localisation of tuberculosis. Generalised (milliary) TB. TB meningitis. TB of
peripheral lymph nodes. Tuberculous pleurisy.
TB in children. BCG vaccination.
Differences of TB disease in vaccinated and non-vaccinated children.
|
4
|
4.
|
Clinical management of tuberculosis.
Anti-TB medicines. Standardised and individualised regimens of treatment.
Drug-resistant strains of M. tuberculosis: mono-, poly-, MDR and XDR-TB. Active
monitoring and management of adverse events of anti-TB drugs. Recording
standardized treatment outcomes. Fighting TB stigma and
discrimination.
|
4
|
5.
|
Management of TB/HIV co-infection.
Antiretroviral Therapy for Patients with HIV and Active Tuberculosis. Tuberculosis-Associated
Immune Reconstitution Inflammatory Syndrome. Surgical treatment of TB.
Palliative care. Directly Observed Therapy.. Adherence to treatment.
|
4
|
6.
|
Prevention of tuberculosis. Infection
Control: administrative, engineering and respiratory protection levels.
Contact Tracing. BCG Vaccination. Preventive chemotherapy. TB health care
policy.
|
4
|
7.
|
BCG Vaccination. Management and outcome
of Bacille Calmette-Guérin vaccine adverse reactions. Preventive Therapy for
Tuberculous Infection. When Is the Benefit Worth the Risk and
Cost?
|
4
|
Module
|
||
Total
|
28
|