Thematic plan of the lessons in Phthisiology for IV year students of stomatology faculty

THE PROGRAMME
OF PRACTICAL SEMINARS
 “Phthisiology” for dental students

Topic
Hours
1.
The causative agent of tuberculosis (TB), structure, metabolism, pathogenesis and molecular determinants of virulence. Classification of Mycobacterium species. Epidemiological indicators of TB burden. Global and national TB epidemiology. TB transmission. Pathogenesis of tuberculosis. Immunity to TB. Clinical classification of tuberculosis. Latent TB infection. Risk groups. Primary and Post Primary TB.


4
2.
Clinical presentation of TB. Cough management in primary care settings. Laboratory diagnostics of tuberculosis. Sputum AFB microscopy. Rules of specimen’s collection. Bacteriological and molecular methods of detection of M. tuberculosis. Benefits and drawbacks of phenotypic and genotypic lab methods. Chest radiography, CT scanning and MRI in TB detection. Descriptive terminology and types of imaging. Typical and atypical presentations of Pulmonary TB on a Chest X-Ray. Tuberculin Skin Test (TST). Interferon-Gamma Release Assays (IGRA). Interpretation of TST and IGRA results. Other tools to confirm TB diagnosis. Life-threatening complications of TB requiring Intensive Care Unit (ICU) admission: pneumothorax, lung hemorrhage, airway obstruction, anaphylaxis.



4
3.
Pulmonary, extrapulmonary, and combined localisation of tuberculosis. Generalised (milliary) TB. TB meningitis. TB of peripheral lymph nodes. Tuberculous pleurisy.
TB in children. BCG vaccination. Differences of TB disease in vaccinated and non-vaccinated children.
4

4.
Clinical management of tuberculosis. Anti-TB medicines. Standardised and individualised regimens of treatment. Drug-resistant strains of M. tuberculosis: mono-, poly-, MDR and XDR-TB. Active monitoring and management of adverse events of anti-TB drugs. Recording standardized treatment outcomes. Fighting TB stigma and discrimination.

4
5.
Management of TB/HIV co-infection. Antiretroviral Therapy for Patients with HIV and Active Tuberculosis. Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome. Surgical treatment of TB. Palliative care. Directly Observed Therapy.. Adherence to treatment.

4
6.
Prevention of tuberculosis. Infection Control: administrative, engineering and respiratory protection levels. Contact Tracing. BCG Vaccination. Preventive chemotherapy. TB health care policy.


4
7.
BCG Vaccination. Management and outcome of Bacille Calmette-Guérin vaccine adverse reactions. Preventive Therapy for Tuberculous Infection. When Is the Benefit Worth the Risk and Cost?


4

Module


Total
28

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